Pluripotency factors select gene expression repertoire at Zygotic Genome Activation
Meijiang Gao, Marina Veil, Marcus Rosenblatt, Anna Gebhard, Helge Hass, Lenka Buryanova, Lev Y. Yampolsky, Björn Grüning, Jens Timmer, Daria Onichtchouk
Under Consideration
Preprints currently under consideration.
Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and recognition
Alice L. B. Pyne, Agnes Noy, Kavit Main, Victor Velasco-Berrelleza, Michael M. Piperakis, Lesley A. Mitchenhall, Fiorella M. Cugliandolo, Joseph G. Beton, Clare E. M. Stevenson, Bart W. Hoogenboom, Andrew D. Bates, Anthony Maxwell, Sarah A. Harris
Congenital disorder of glycosylation caused by starting site specific variant in syntaxin-5
Peter Linders, Eveline Gerretsen, Angel Ashikov, Mari-Anne Vals, Natalia H Revelo, Richard Arts, Melissa Baerenfaenger, Fokje Zijlstra, Karin Huijben, Kimiyo Raymond, Kai Muru, Olga Fjodorova, Sander Pajusalu, Katrin Õunap, Martin ter Beest, Dirk Lefeber, Geert van den Bogaart
TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration
Wei Qiao, Karen H.M. Wong, Jie Shen, Wenhao Wang, Jun Wu, Jinhua Li, Zhengjie Lin, Zetao Chen, Jukka P. Matinlinna, Yufeng Zheng, Shuilin Wu, Xuanyong Liu, Keng Po Lai, Zhuofan Chen, Yun Wah Lam, Kenneth M.C. Cheung, Kelvin W.K. Yeung
Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity, enabling mutant p53 stabilization and invasion
Oezge Cicek Sener, Adrian Stender, Luisa Klemke, Nadine Stark, Tamara Isermann, Jinyu Li, Ute Martha Moll, Ramona Schulz-Heddergott
Environmentally sensitive hotspots in the methylome of the early human embryo
Matt J Silver, Ayden Saffari, Noah J Kessler, Giriraj R Chandak, Caroline HD Fall, Prachand Issarapu, Akshay Dedaniya, Modupeh Betts, Sophie E Moore, Philip T James, David Monk, Andrew M Prentice
Proliferation control of kidney interstitial cells
Sarah S. McCarthy, Lindsey Gower, Michele Karolak, Alicia England, Thomas Carroll, Leif Oxburgh
Canonical and noncanonical features of the mouse visual cortical hierarchy
Rinaldo D. D’Souza, Quanxin Wang, Weiqing Ji, Andrew M. Meier, Henry Kennedy, Kenneth Knoblauch, Andreas Burkhalter
Age-Dependent Changes in the Progenitor Translatome Coordinated in part by Tsc1 Increase Perception of Signaling Inputs to End Nephrogenesis
Eric Brunskill, Alison Jarmas, Praneet Chaturvedi, Raphael Kopan
Unsupervised graph-based learning predicts mutations that alter protein dynamics
Robert L. Peach, Dominik Saman, Sophia N. Yaliraki, David R. Klug, Liming Ying, Keith R. Willison, Mauricio Barahona
Multimodal brain imaging study of 19,825 participants reveals adverse effects of moderate drinking
Remi Daviet, Gökhan Aydogan, Kanchana Jagannathan, Nathaniel Spilka, Philipp Koellinger, Henry R Kranzler, Gideon Nave, Reagan Wetherill
Thioesterase Superfamily Member 1 Undergoes Stimulus-coupled Reorganization to Regulate Metabolism
Yue Li, Norihiro Imai, Samaksh Goyal, Hayley T. Nicholls, Tibor I. Krisko, Mahnoor Baqai, Lay-Hong Ang, Matthew C. Tillman, Eric A. Ortlund, David E. Cohen, Susan J. Hagen
The serine-threonine kinase TAO3 promotes cancer invasion and tumor growth by facilitating trafficking of endosomes containing the invadopodia scaffold TKS5a
Shinji Iizuka, Manuela Quintavalle, Jose Ceja Navarro, Kyle P. Gribbin, Robert J. Ardecky, Matthew Abelman, Chen-Ting Ma, Eduard Sergienko, Fu-Yue Zeng, Ian Pass, George Thomas, Shannon McWeeney, Christian A. Hassig, Anthony B Pinkerton, Sara A Courtneidge
Succinylation Links Metabolic Reductions to Amyloid and Tau Pathology
Yun Yang, Victor Tapias, Diana Acosta, Hui Xu, Huanlian Chen, Ruchika Bhawal, Elizabeth Anderson, Elena Ivanova, Hening Lin, Botir T. Sagdullaev, William L. Klein, Kirsten L. Viola, Sam Gandy, Vahram Haroutunian, M. Flint Beal, David Eliezer, Sheng Zhang, Gary E. Gibson
Bacteroides uniformis enhances endurance exercise performance through gluconeogenesis
Hiroto Morita, Chie Kano, Chiharu Ishii, Noriko Kagata, Takamasa Ishikawa, Yoshihide Uchiyama, Susumu Hara, Teppei Nakamura, Shinji Fukuda
Genome-wide targets identification by CRISPRi-Omics for high-titer production of free fatty acids in Escherichia coli
Lixia Fang, Jie Fan, Congya Wang, Yingxiu Cao, Hao Song
Intracellular Lipid Droplet Accumulation Occurs Early Following Viral Infection and Is Required for an Efficient Interferon Response
Ebony A Monson, Keaton M Crosse, Erika Duan, Weisan Chen, Ross D O'Shea, Linda M Wakem, Donna R Whelan, Karla J Helbig