Mediator subunit Med15 dictates the conserved “fuzzy” binding mechanism of yeast transcription activators Gal4 and Gcn4
Lisa M. Tuttle, Derek Pacheco, Linda Warfield, Steven Hahn, Rachel E. Klevit
Under Consideration
Preprints currently under consideration.
Machine learning accurate exchange and correlation functionals of the electronic density
Sebastian Dick and Marivi Fernandez-Serra
Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation
Aurelie Bertin, Nicola de Franceschi, Eugenio de la Mora, Sourav maity, Nolwen Miguet, Aurelie di Cicco, Wouter H Roos, Stephanie Mangenot, Winfried Weissenhorn, Patricia Bassereau
The receptor PTPRU is a redox sensitive pseudophosphatase
ain M. Hay, Gareth W. Fearnley, Pablo Rios, Maja Köhn, Hayley J. Sharpe, Janet E. Deane
Senescence and entrenchment in evolution of amino acid sites
A. V. Stolyarova, E. Nabieva, V. V. Ptushenko, A. V. Favorov, A. V. Popova, A. D. Neverov, G. A. Bazykin
Dynamical informational structures characterize the different human brain states of wakefulness and deep sleep
Javier Alejandro Galadi, Silvana Silva Pereira, Yonantan Sanz Perl, Morten L Kringelbach, Inmaculada Gayte, Helmut Laufs, Enzo Tagliazucchi, Jose Antonio Langa, Gustavo Deco
Mapping cellular-scale internal stiffness in 3D tissues with smart material hydrogel probes
Stephanie Mok, Sara Al Habyan, Charles Ledoux, Wontae Lee, Katherine MacDonald, Luke McCaffrey, Christopher Moraes
Spin-phonon relaxation in disparate materials from a universal ab initio density matrix approach
Junqing Xu, Adela Habib, Sushant Kumar, Feng Wu, Ravishankar Sundararaman, Yuan Ping
Hippocampus has lower oxygenation and weaker control of brain blood flow than cortex, due to microvascular differences
K. Shaw, L. Bell, K. Boyd, D.M. Grijseels, D. Clarke, O. Bonnar, H.S. Crombag, C.N. Hall
A Domain-agnostic, Noise-resistant, Hardware-efficient Evolutionary Variational Quantum Eigensolver
Arthur G. Rattew, Shaohan Hu, Marco Pistoia, Richard Chen and Steve Wood
Real-time tracking reveals the catalytic process of Rad51-driven DNA strand exchange
Kentaro Ito, Yasuto Murayama, Yumiko Kurokawa, Shuji Kanamaru, Yuichi Kokabu, Takahisa Maki, Bilge Argunhan, Hideo Tsubouchi, Mitsunori Ikeguchi, Masayuki Takahashi and Hiroshi Iwasaki
Biosynthesis of the redox cofactor mycofactocin comprises oligoglycosylation by MftF in Mycolicibacterium smegmatis
Luis Peña-Ortiz, Ana Patrícia Graça, Huijuan Guo, Daniel Braga, Tobias G. Köllner, Lars Regestein, Christine Beemelmanns and Gerald Lackner
PharmOmics: A Species- and Tissue-specific Drug Signature Database and Online Tool for Toxicity Prediction and Drug Repurposing
Yen-Wei Chen, Douglas Arneson, Graciel Diamente, Jennifer Garcia, Nima Zaghari, Paul Patel, Patrick Allard, and Xia Yang
Escape from nonsense mediated decay associates with anti-tumor immunogenicity
Kevin Litchfield, James Reading, Emilia Lim, Hang Xu, Po Liu, Maise AL-Bakir, Sophia Wong, Andrew Rowan, Sam Funt, Taha Merghoub, Martin Lauss, Inge Marie Svane, Göran Jönsson, Javier Herrero, James Larkin, Sergio A. Quezada, Matthew D. Hellmann, Samra Turajlic, Charles Swanton
Functional 3D architecture in an intrinsically disordered E3 ligase domain facilitates ubiquitin transfer
Paul Murphy, Yingqi Xu, Sarah L. Rouse, Steve J. Matthews, J Carlos Penedo and Ronald T. Hay
The M-phase regulatory phosphatase PP2A-B55d opposes protein kinase A on Arpp19 to initiate meiotic division
Tom Lemonnier, Enrico Maria Daldello, Robert Poulhe, Tran Le, Marika Miot, Catherine
Jessus, Aude Dupré
Dual RNA-seq provides insight into the biology of the neglected intracellular human pathogen Orientia tsutsugamushi
Bozena Mika-Gospodorz, Suparat Giengkam, Alexander J. Westermann, Jantana Wongsantichon, Willow Kion-Crosby, Suthida Chuenklin, Loo Chien Wang, Piyanate Sunyakumthorn, Radoslaw M. Sobota, Selvakumar Subbian, Jörg Vogel, Lars Barquist, Jeanne Salje
Transcriptomic learning for digital pathology
Benoît Schmauch, Alberto Romagnoni, Elodie Pronier, Charlie Saillard, Pascale Maillé, Julien Calderaro, Meriem Sefta, Sylvain Toldo, Mikhail Zaslavskiy, Thomas Clozel, Matahi Moarii, Pierre Courtiol, Gilles Wainrib
An enhancer:involucrin regulatory module impacts human skin barrier adaptation out-of-Africa and modifies atopic dermatitis risk
Mary Elizabeth Mathyer, Erin A. Brettmann, Alina D. Schmidt, Zane A. Goodwin, Ashley M. Quiggle, Inez Y. Oh, Eric Tycksen, Lisa Zhou, Yeriel D. Estrada, X.F. Colin C. Wong, Simon L.I.J. Denil, Scot A. Matkovich, Avner Shemer, John E. A. Common, Emma Guttman-Yassky, Cristina de Guzman Strong