Nature Communications
<p><em>Nature Communications</em> is an open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences. Papers published by the journal aim to represent important advances of significance to specialists within each field.</p>
<p>We are committed to providing an efficient service for both authors and readers. Our team of independent editors make rapid and fair publication decisions. Prompt dissemination of accepted papers to a wide readership and beyond is achieved through a programme of continuous online publication. </p>
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Nature Communications
© 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
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Nature Communications
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https://www.nature.com/articles/s41467-024-46922-4
Nature Communications, Published online: 29 March 2024; doi:10.1038/s41467-024-46922-4Here, the authors have determined structures of 753b PROTAC, BCL-xL/BCL-2 and VHL E3 ligase ternary complexes which reveal the basis for the dual degrader activity of 753b. The structures and subsequent functional analyses facilitated design of WH244 PROTAC, with enhanced degrader activity in cells.]]>
Digant NayakDongwen LvYaxia YuanPeiyi ZhangWanyi HuAnindita NayakEliza A. RubenZongyang LvPatrick SungRobert HromasGuangrong ZhengDaohong ZhouShaun K. Olsen
doi:10.1038/s41467-024-46922-4
Nature Communications, Published online: 2024-03-29; | doi:10.1038/s41467-024-46922-4
2024-03-29
Nature Communications
10.1038/s41467-024-46922-4
https://www.nature.com/articles/s41467-024-46922-4
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https://www.nature.com/articles/s41467-024-47076-z
Nature Communications, Published online: 29 March 2024; doi:10.1038/s41467-024-47076-zThree-dimensional carbon microstructures with ultra-high aspect ratios are grown with a facile process using a metal-free catalyst and low-power visible light at room temperature, unlocking applications in flexible sensors and beyond.]]>
Fernand E. Torres-DavilaKaterina L. ChagoyaEmma E. BlancoSaqib ShahzadLorianne R. Shultz-JohnsonMirra MogensenAndre GesquiereTitel JurcaNabil RochdiRichard G. BlairLaurene Tetard
doi:10.1038/s41467-024-47076-z
Nature Communications, Published online: 2024-03-29; | doi:10.1038/s41467-024-47076-z
2024-03-29
Nature Communications
10.1038/s41467-024-47076-z
https://www.nature.com/articles/s41467-024-47076-z
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https://www.nature.com/articles/s41467-024-46977-3
Nature Communications, Published online: 29 March 2024; doi:10.1038/s41467-024-46977-3Chest computed tomography (CT) is one of the most common diagnostic tests. Here, the authors combine two AI models to measure from CT coronary artery calcium, left ventricular mass index, and left and right atrial and ventricular volumes, and show their association with cardiovascular mortality.]]>
Robert J. H. MillerAditya KillekarAakash ShanbhagBryan BednarskiAnna M. MichalowskaTerrence D. RuddyAndrew J. EinsteinDavid E. NewbyMark LemleyKonrad PieszkoSerge D. Van KriekingePaul B. KavanaghJoanna X. LiangCathleen HuangDamini DeyDaniel S. BermanPiotr J. Slomka
doi:10.1038/s41467-024-46977-3
Nature Communications, Published online: 2024-03-29; | doi:10.1038/s41467-024-46977-3
2024-03-29
Nature Communications
10.1038/s41467-024-46977-3
https://www.nature.com/articles/s41467-024-46977-3
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Acinetobacter type IV pili targeting by an RNA virus]]>
https://www.nature.com/articles/s41467-024-47119-5
Nature Communications, Published online: 29 March 2024; doi:10.1038/s41467-024-47119-5Here, the authors structurally characterise the interaction between Acinetobacter phage AP205 and the type IV Acinetobacter pili using cryo-electron microscopy, uncovering the mechanistic determinants of this interaction.]]>
Acinetobacter type IV pili targeting by an RNA virus]]>
Ran MengZhongliang XingJeng-Yih ChangZihao YuJirapat ThongcholWen XiaoYuhang WangKarthik ChamakuraZhiqi ZengFengbin WangRy YoungLanying ZengJunjie Zhang
doi:10.1038/s41467-024-47119-5
Nature Communications, Published online: 2024-03-29; | doi:10.1038/s41467-024-47119-5
2024-03-29
Nature Communications
10.1038/s41467-024-47119-5
https://www.nature.com/articles/s41467-024-47119-5
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https://www.nature.com/articles/s41467-024-47158-y
Nature Communications, Published online: 29 March 2024; doi:10.1038/s41467-024-47158-yCombining experimental lineage tracing with single cell transcriptomics is technically demanding. Here, authors present GEMLI, a computational tool to annotate cell lineages in single cell RNA sequencing data solely based on gene expression.]]>
A. S. EiseleM. TarbierA. A. DormannV. PelechanoD. M. Suter
doi:10.1038/s41467-024-47158-y
Nature Communications, Published online: 2024-03-29; | doi:10.1038/s41467-024-47158-y
2024-03-29
Nature Communications
10.1038/s41467-024-47158-y
https://www.nature.com/articles/s41467-024-47158-y
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ATG16L1 polymorphism is associated with improved clinical outcome and T-cell immunity in chronic HIV-1 infection]]>
https://www.nature.com/articles/s41467-024-46606-z
Nature Communications, Published online: 28 March 2024; doi:10.1038/s41467-024-46606-zT cell dysregulation is a hallmark of chronic HIV-1 infection that is partially restored by antiretroviral therapy. Here the authors show that ATG16L1 rs6861 polymorphism is associated clinically with prolonged control of disease pathogenesis, and functionally with enhanced autophagy and T-cell immunity in chronically HIV-1 infected individuals.]]>
ATG16L1 polymorphism is associated with improved clinical outcome and T-cell immunity in chronic HIV-1 infection]]>
Renée R. C. E. SchreursAthanasios KoulisThijs BooimanBrigitte Boeser-NunninkAlexandra P. M. ClohertyAnusca G. RaderKharishma S. PatelNeeltje A. KootstraCarla M. S. Ribeiro
doi:10.1038/s41467-024-46606-z
Nature Communications, Published online: 2024-03-28; | doi:10.1038/s41467-024-46606-z
2024-03-28
Nature Communications
10.1038/s41467-024-46606-z
https://www.nature.com/articles/s41467-024-46606-z
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https://www.nature.com/articles/s41467-024-46908-2
Nature Communications, Published online: 28 March 2024; doi:10.1038/s41467-024-46908-2The authors achieve enhanced cavity loading using complex-frequency excitations that can tailor on-demand the effective coupling rate in a microring resonator by precisely controlling the temporal evolution of the incident pulses.]]>
Jakob HinneySeunghwi KimGraydon J. K. FlattIpshita DattaAndrea AlùMichal Lipson
doi:10.1038/s41467-024-46908-2
Nature Communications, Published online: 2024-03-28; | doi:10.1038/s41467-024-46908-2
2024-03-28
Nature Communications
10.1038/s41467-024-46908-2
https://www.nature.com/articles/s41467-024-46908-2
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https://www.nature.com/articles/s41467-024-46757-z
Nature Communications, Published online: 28 March 2024; doi:10.1038/s41467-024-46757-zThe effect of biogeographic isolation on biodiversity remains unclear. Assessing global mammal and bird assemblages, the authors show that long-term biogeographic barriers explain reduced species richness and divergent ecological function, while environment determines diversity in most of the world.]]>
Peter J. WilliamsElise F. ZipkinJedediah F. Brodie
doi:10.1038/s41467-024-46757-z
Nature Communications, Published online: 2024-03-28; | doi:10.1038/s41467-024-46757-z
2024-03-28
Nature Communications
10.1038/s41467-024-46757-z
https://www.nature.com/articles/s41467-024-46757-z