Nature Communications <p><em>Nature Communications</em>&nbsp;is an open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences. Papers published by the journal aim to represent important advances of significance to specialists within each field.</p> <p>We are committed to providing an efficient service for both authors and readers. Our&nbsp;team of independent editors make rapid and fair publication decisions. Prompt dissemination of accepted papers to a&nbsp;wide readership and beyond is achieved through a programme of continuous online publication.&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;</p> http://feeds.nature.com/ncomms/rss/current Nature Publishing Group en © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature Communications © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com Nature Communications https://www.nature.com/uploads/product/ncomms/rss.png http://feeds.nature.com/ncomms/rss/current <![CDATA[Prediction of glycopeptide fragment mass spectra by deep learning]]> https://www.nature.com/articles/s41467-024-46771-1 Nature Communications, Published online: 19 March 2024; doi:10.1038/s41467-024-46771-1

Deep learning has achieved a notable success in proteomics and is now emerging in glycoproteomics. Here, the authors develop a neural network-based method to predict mass spectra of intact glycopeptides and demonstrate its potential in data-dependent and data-independent acquisition glycoproteomics.]]>
Yi YangQun Fang doi:10.1038/s41467-024-46771-1 Nature Communications, Published online: 2024-03-19; | doi:10.1038/s41467-024-46771-1 2024-03-19 Nature Communications 10.1038/s41467-024-46771-1 https://www.nature.com/articles/s41467-024-46771-1
<![CDATA[Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial]]> https://www.nature.com/articles/s41467-024-45835-6 Nature Communications, Published online: 19 March 2024; doi:10.1038/s41467-024-45835-6

Intrinsic and acquired resistances to CDK4/6 inhibitors have been described in patients with breast cancer. Here the authors report the results from a phase I/II clinical trial of the aromatase inhibitor exemestane plus everolimus (mTOR inhibitor) and palbociclib (CDK4/6i) in patients with metastatic breast cancer, assessing safety, clinical efficacy, as well as genomic and transcriptomic determinants of resistance.]]>
Jorge Gómez Tejeda ZañudoRomualdo Barroso-SousaEsha JainQingchun JinTianyu LiJorge E. Buendia-BuendiaAlyssa PeresleteDaniel L. AbravanelArlindo R. FerreiraEileen WrabelKarla HelvieMelissa E. HughesAnn H. PartridgeBeth OvermoyerNancy U. LinNabihah TayobSara M. TolaneyNikhil Wagle doi:10.1038/s41467-024-45835-6 Nature Communications, Published online: 2024-03-19; | doi:10.1038/s41467-024-45835-6 2024-03-19 Nature Communications 10.1038/s41467-024-45835-6 https://www.nature.com/articles/s41467-024-45835-6
<![CDATA[Face and context integration in emotion inference is limited and variable across categories and individuals]]> https://www.nature.com/articles/s41467-024-46670-5 Nature Communications, Published online: 19 March 2024; doi:10.1038/s41467-024-46670-5

People infer emotions using faces and situations, yet little is known about how these are integrated. Here, the authors show that situations are often sufficient to infer emotions, with variability in integration across categories and individuals.]]>
Srishti GoelJulian Jara-EttingerDesmond C. OngMaria Gendron doi:10.1038/s41467-024-46670-5 Nature Communications, Published online: 2024-03-19; | doi:10.1038/s41467-024-46670-5 2024-03-19 Nature Communications 10.1038/s41467-024-46670-5 https://www.nature.com/articles/s41467-024-46670-5
<![CDATA[In-section Click-iT detection and super-resolution CLEM analysis of nucleolar ultrastructure and replication in plants]]> https://www.nature.com/articles/s41467-024-46324-6 Nature Communications, Published online: 19 March 2024; doi:10.1038/s41467-024-46324-6

Application of correlative light and electron microscopy (CLEM) in plants remains challenging. Here, the authors use Click-iT chemistry as a tool for CLEM, due to its unique properties in resin permeability and super-resolution microscopy. They use this approach to study cellular physiology in Arabidopsis.]]>
Michal FranekLenka KoptašíkováJíří MikšátkoDavid LieblEliška MacíčkováJakub PospíšilMilan EsnerMartina DvořáčkováJíří Fajkus doi:10.1038/s41467-024-46324-6 Nature Communications, Published online: 2024-03-19; | doi:10.1038/s41467-024-46324-6 2024-03-19 Nature Communications 10.1038/s41467-024-46324-6 https://www.nature.com/articles/s41467-024-46324-6
<![CDATA[Tradeoffs in alignment and assembly-based methods for structural variant detection with long-read sequencing data]]> https://www.nature.com/articles/s41467-024-46614-z Nature Communications, Published online: 19 March 2024; doi:10.1038/s41467-024-46614-z

Long-read sequencing can greatly improve detection of genomic structural variants (SVs), and numerous methods have been developed to identify SVs using long-read data. Here the authors compare the performance of these methods and provide guidelines to aid users in selecting the most suitable tools for various scenarios.]]>
Yichen Henry LiuCan LuoStaunton G. GoldingJacob B. IoffeXin Maizie Zhou doi:10.1038/s41467-024-46614-z Nature Communications, Published online: 2024-03-19; | doi:10.1038/s41467-024-46614-z 2024-03-19 Nature Communications 10.1038/s41467-024-46614-z https://www.nature.com/articles/s41467-024-46614-z
<![CDATA[Long-term effects of Omicron BA.2 breakthrough infection on immunity-metabolism balance: a 6-month prospective study]]> https://www.nature.com/articles/s41467-024-46692-z Nature Communications, Published online: 19 March 2024; doi:10.1038/s41467-024-46692-z

Here the authors study recovery from mild to moderate Omicron breakthrough infection at six months post infection. Serum proteomics, PBMC single-cell transcriptomics and clinical parameters indicate slow recovery with coagulation abnormalities and an imbalance of the immune response and metabolism remaining.]]>
Yanhua LiShijie QinLei DongShitong QiaoXiao WangDongshan YuPengyue GaoYali HouShouzhen QuanYing LiFengyan FanXin ZhaoYueyun MaGeorge Fu Gao doi:10.1038/s41467-024-46692-z Nature Communications, Published online: 2024-03-19; | doi:10.1038/s41467-024-46692-z 2024-03-19 Nature Communications 10.1038/s41467-024-46692-z https://www.nature.com/articles/s41467-024-46692-z
<![CDATA[Publisher Correction: A programmable hybrid digital chemical information processor based on the Belousov-Zhabotinsky reaction]]> https://www.nature.com/articles/s41467-024-46859-8 Nature Communications, Published online: 18 March 2024; doi:10.1038/s41467-024-46859-8

Publisher Correction: A programmable hybrid digital chemical information processor based on the Belousov-Zhabotinsky reaction]]>
Abhishek SharmaMarcus Tze-Kiat NgJuan Manuel Parrilla GutierrezYibin JiangLeroy Cronin doi:10.1038/s41467-024-46859-8 Nature Communications, Published online: 2024-03-18; | doi:10.1038/s41467-024-46859-8 2024-03-18 Nature Communications 10.1038/s41467-024-46859-8 https://www.nature.com/articles/s41467-024-46859-8
<![CDATA[Population imaging cerebellar growth for personalized neuroscience]]> https://www.nature.com/articles/s41467-024-46545-9 Nature Communications, Published online: 18 March 2024; doi:10.1038/s41467-024-46545-9

Growth chart studies of the human cerebellum, which is increasingly recognized as pivotal for cognitive development, are rare. Gaiser and colleagues utilized population-level neuroimaging to unveil cerebellar growth charts from childhood to adolescence, offering insights into brain development.]]>
Zi-Xuan ZhouXi-Nian Zuo doi:10.1038/s41467-024-46545-9 Nature Communications, Published online: 2024-03-18; | doi:10.1038/s41467-024-46545-9 2024-03-18 Nature Communications 10.1038/s41467-024-46545-9 https://www.nature.com/articles/s41467-024-46545-9